Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50315846'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50315846 (5-(pyridin-4-yl)-6-(pyrrolidin-1-yl)-3-styryl-1H-i...) Show SMILES C1CCN(C1)c1cc2[nH]nc(\C=C\c3ccccc3)c2cc1-c1ccncc1 Show InChI InChI=1S/C24H22N4/c1-2-6-18(7-3-1)8-9-22-21-16-20(19-10-12-25-13-11-19)24(17-23(21)27-26-22)28-14-4-5-15-28/h1-3,6-13,16-17H,4-5,14-15H2,(H,26,27)/b9-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
S*BIO Pte. Ltd Curated by ChEMBL					Assay Description Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescence				Bioorg Med Chem Lett 20: 2443-7 (2010) Article DOI: 10.1016/j.bmcl.2010.03.018 BindingDB Entry DOI: 10.7270/Q24B31HK
					More data for this Ligand-Target Pair