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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50315852'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50315852
PNG
(CHEMBL1090910 | N-(3-phenethyl-1H-indazol-5-yl)-2-...)
Show SMILES O=C(Cc1ccccc1)Nc1ccc2[nH]nc(CCc3ccccc3)c2c1
Show InChI InChI=1S/C23H21N3O/c27-23(15-18-9-5-2-6-10-18)24-19-12-14-22-20(16-19)21(25-26-22)13-11-17-7-3-1-4-8-17/h1-10,12,14,16H,11,13,15H2,(H,24,27)(H,25,26)
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MMDB

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Similars
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



S*BIO Pte. Ltd

Curated by ChEMBL


Assay Description
Inhibition of hexahistidine tagged recombinant Aurora A expressed in Hi-5 cells assessed as ATP remaining after 2 hrs by bioluminnescence

Bioorg Med Chem Lett 20: 2443-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.018
BindingDB Entry DOI: 10.7270/Q24B31HK
More data for this
Ligand-Target Pair