Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50318580'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50318580 (4-(6-Bromo-2-(4-(dimethylamino)phenyl)-3H-imidazo[...) Show SMILES CN(C)c1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(CC3)C(=O)Nc3ccccc3)c2[nH]1 Show InChI InChI=1S/C25H26BrN7O/c1-31(2)19-10-8-17(9-11-19)23-29-21-22(20(26)16-27-24(21)30-23)32-12-14-33(15-13-32)25(34)28-18-6-4-3-5-7-18/h3-11,16H,12-15H2,1-2H3,(H,28,34)(H,27,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	277	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant Aurora A expressed in baculovirus system				J Med Chem 53: 5213-28 (2010) Article DOI: 10.1021/jm100262j BindingDB Entry DOI: 10.7270/Q2GB251P
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