Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50318591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50318591 (6-Bromo-7-[4-(4-chlorobenzyl)-piperazin-1-yl]-2-(4...) Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4ccc(Cl)cc4)CC3)c2[nH]1 Show InChI InChI=1S/C24H23BrClN5O/c1-32-19-8-4-17(5-9-19)23-28-21-22(20(25)14-27-24(21)29-23)31-12-10-30(11-13-31)15-16-2-6-18(26)7-3-16/h2-9,14H,10-13,15H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of human recombinant Aurora A expressed in baculovirus system				J Med Chem 53: 5213-28 (2010) Article DOI: 10.1021/jm100262j BindingDB Entry DOI: 10.7270/Q2GB251P
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50318591 (6-Bromo-7-[4-(4-chlorobenzyl)-piperazin-1-yl]-2-(4...) Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4ccc(Cl)cc4)CC3)c2[nH]1 Show InChI InChI=1S/C24H23BrClN5O/c1-32-19-8-4-17(5-9-19)23-28-21-22(20(25)14-27-24(21)29-23)31-12-10-30(11-13-31)15-16-2-6-18(26)7-3-16/h2-9,14H,10-13,15H2,1H3,(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair