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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50318609'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50318609
PNG
(3-((4-(6-Bromo-2-(4-(piperazin-1-yl)phenyl)-3H-imi...)
Show SMILES Cc1cc(CN2CCN(CC2)c2c(Br)cnc3nc([nH]c23)N2CCNCC2)no1
Show InChI InChI=1S/C19H25BrN8O/c1-13-10-14(25-29-13)12-26-6-8-27(9-7-26)17-15(20)11-22-18-16(17)23-19(24-18)28-4-2-21-3-5-28/h10-11,21H,2-9,12H2,1H3,(H,22,23,24)
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Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Aurora A expressed in baculovirus system

J Med Chem 53: 5213-28 (2010)


Article DOI: 10.1021/jm100262j
BindingDB Entry DOI: 10.7270/Q2GB251P
More data for this
Ligand-Target Pair