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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50335338'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50335338
PNG
(4-(5-Methyl-1H-pyrazol-3-ylamino)-2-[2-oxo-2-(4-tr...)
Show SMILES Cc1cc(Nc2nn(CC(=O)c3ccc(cc3)C(F)(F)F)c(=O)c3ccccc23)[nH]n1
Show InChI InChI=1S/C21H16F3N5O2/c1-12-10-18(27-26-12)25-19-15-4-2-3-5-16(15)20(31)29(28-19)11-17(30)13-6-8-14(9-7-13)21(22,23)24/h2-10H,11H2,1H3,(H2,25,26,27,28)
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MMDB

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Article
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n/an/a 720n/an/an/an/an/an/a



Evotec (UK) Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Aurora A by ELISA

J Med Chem 54: 312-9 (2011)


Article DOI: 10.1021/jm101346r
BindingDB Entry DOI: 10.7270/Q29P32MB
More data for this
Ligand-Target Pair