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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50335615'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))
BDBM50335615
PNG
(6-bromo-2-(4-methoxyphenyl)-7-(4-(pyridin-4-ylmeth...)
Show SMILES COc1ccc(cc1)-c1nc2ncc(Br)c(N3CCN(Cc4ccncc4)CC3)c2[nH]1
Show InChI InChI=1S/C23H23BrN6O/c1-31-18-4-2-17(3-5-18)22-27-20-21(19(24)14-26-23(20)28-22)30-12-10-29(11-13-30)15-16-6-8-25-9-7-16/h2-9,14H,10-13,15H2,1H3,(H,26,27,28)
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MMDB

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Article
PubMed
n/an/a 9n/an/an/an/an/an/a



Jinan University

Curated by ChEMBL


Assay Description
Inhibition of Aurora A


Eur J Med Chem 46: 77-94 (2010)


Article DOI: 10.1016/j.ejmech.2010.10.017
BindingDB Entry DOI: 10.7270/Q25X296N
More data for this
Ligand-Target Pair