Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50352493'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50352493 (CHEMBL1824334) Show SMILES COc1ccc(CNC(=O)Nc2cc(ccn2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C15H15N7O2/c1-24-12-4-2-10(3-5-12)9-17-15(23)18-13-8-11(6-7-16-13)14-19-21-22-20-14/h2-8H,9H2,1H3,(H2,16,17,18,23)(H,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+8	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Darmstadt Curated by ChEMBL					Assay Description Inhibition of human AURKA activity using Ser/Thr 1 peptide as substrate by FRET assay				Bioorg Med Chem Lett 21: 5610-5 (2011) Article DOI: 10.1016/j.bmcl.2011.06.131 BindingDB Entry DOI: 10.7270/Q2765FP3
					More data for this Ligand-Target Pair