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Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50353275'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50353275
PNG
(CHEMBL1830680)
Show SMILES O=S(=O)(c1ccccc1)c1cnc2ncnn2c1-c1ccccc1
Show InChI InChI=1S/C17H12N4O2S/c22-24(23,14-9-5-2-6-10-14)15-11-18-17-19-12-20-21(17)16(15)13-7-3-1-4-8-13/h1-12H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 104n/an/an/an/an/an/a



Umm Al-Qura University

Curated by ChEMBL


Assay Description
Inhibition of GST-tagged Aurora A kinase expressed in insect cells assessed as inhibition of [33P]gamma-ATP incorporation in substrate after 60 mins ...

Eur J Med Chem 46: 3690-5 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.033
BindingDB Entry DOI: 10.7270/Q2FX7BFK
More data for this
Ligand-Target Pair