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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50389256'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50389256
PNG
(CHEMBL2063465)
Show SMILES Nc1ncnn2ccc(C(=O)Nc3ccc(NC(=O)Nc4ccc(F)cc4)cc3)c12
Show InChI InChI=1S/C20H16FN7O2/c21-12-1-3-14(4-2-12)26-20(30)27-15-7-5-13(6-8-15)25-19(29)16-9-10-28-17(16)18(22)23-11-24-28/h1-11H,(H,25,29)(H2,22,23,24)(H2,26,27,30)
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Article
PubMed
n/an/a 88n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Aurora A kinase by HTRF analysis in presence of 1 mM ATP

Bioorg Med Chem Lett 22: 4528-31 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.125
BindingDB Entry DOI: 10.7270/Q2T154RT
More data for this
Ligand-Target Pair