Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50426740'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50426740 (CHEMBL2322140) Show SMILES C1CCC(CC1)N1CCCc2cnc3[nH]ccc3c12 Show InChI InChI=1S/C16H21N3/c1-2-6-13(7-3-1)19-10-4-5-12-11-18-16-14(15(12)19)8-9-17-16/h8-9,11,13H,1-7,10H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of Aurora 1 (unknown origin) after 2.5 hrs by time-resolved fluorescence resonance energy transfer assay in presence of 100 uM ATP				Bioorg Med Chem Lett 23: 693-8 (2013) Article DOI: 10.1016/j.bmcl.2012.11.108 BindingDB Entry DOI: 10.7270/Q2DN46CT
					More data for this Ligand-Target Pair