Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM84651'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM84651 (TC-107) Show SMILES OCC=Cc1ccc2ncnc(Nc3cccc(F)c3)c2c1 Show InChI InChI=1S/C17H14FN3O/c18-13-4-1-5-14(10-13)21-17-15-9-12(3-2-8-22)6-7-16(15)19-11-20-17/h1-7,9-11,22H,8H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	7.5	4
Parc de Recerca Biomedica de Barcelona					Assay Description The IC50 for the different compounds was determined with Invitrogen Z'-LYTE kinase assay kit Ser/Thr 1 peptide PV3174 by following the manufactur...				Chembiochem 10: 464-78 (2009) Article DOI: 10.1002/cbic.200800600 BindingDB Entry DOI: 10.7270/Q24F1P8K
					More data for this Ligand-Target Pair