Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM24718'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM24718 (2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole | pyrazole-...) Show SMILES Cc1cc(n[nH]1)-c1cc2ccccc2[nH]1 Show InChI InChI=1S/C12H11N3/c1-8-6-12(15-14-8)11-7-9-4-2-3-5-10(9)13-11/h2-7,13H,1H3,(H,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	7.5	22
Genentech					Assay Description Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...				J Med Chem 51: 4465-75 (2008) Article DOI: 10.1021/jm800052b BindingDB Entry DOI: 10.7270/Q2H70D4F
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