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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50029416'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM50029416
PNG
(CHEMBL3343310)
Show SMILES O=C(NCc1ccccc1)Nc1ccc(Nc2ncnc3cc(OCCCN4CCCCC4)ccc23)cc1
Show InChI InChI=1S/C30H34N6O2/c37-30(31-21-23-8-3-1-4-9-23)35-25-12-10-24(11-13-25)34-29-27-15-14-26(20-28(27)32-22-33-29)38-19-7-18-36-16-5-2-6-17-36/h1,3-4,8-15,20,22H,2,5-7,16-19,21H2,(H2,31,35,37)(H,32,33,34)
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Article
PubMed
n/an/a 193n/an/an/an/an/an/a



Southeast University

Curated by ChEMBL


Assay Description
Inhibition of Aurora-B (unknown origin) using STK substrate 2-biotin by HTRF-KinEASE-STK assay

Bioorg Med Chem 22: 5813-23 (2014)


Article DOI: 10.1016/j.bmc.2014.09.029
BindingDB Entry DOI: 10.7270/Q279468G
More data for this
Ligand-Target Pair