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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50160872'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM50160872
PNG
(CHEMBL3792856)
Show SMILES COC(=O)c1cccc(NC(=O)c2cc(ccc2O)-n2cc(CNc3cc(C)ccn3)nn2)c1
Show InChI InChI=1S/C24H22N6O4/c1-15-8-9-25-22(10-15)26-13-18-14-30(29-28-18)19-6-7-21(31)20(12-19)23(32)27-17-5-3-4-16(11-17)24(33)34-2/h3-12,14,31H,13H2,1-2H3,(H,25,26)(H,27,32)
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Article
PubMed
n/an/a 1.63E+4n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATP

Bioorg Med Chem 24: 2114-24 (2016)


Article DOI: 10.1016/j.bmc.2016.03.042
BindingDB Entry DOI: 10.7270/Q2ZW1NST
More data for this
Ligand-Target Pair