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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50160911'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM50160911
PNG
(CHEMBL3792563)
Show SMILES COC(=O)c1cccc(NC(=O)c2cc(ccc2O)-n2cc(CNc3ccccc3)nn2)c1
Show InChI InChI=1S/C24H21N5O4/c1-33-24(32)16-6-5-9-18(12-16)26-23(31)21-13-20(10-11-22(21)30)29-15-19(27-28-29)14-25-17-7-3-2-4-8-17/h2-13,15,25,30H,14H2,1H3,(H,26,31)
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Article
PubMed
n/an/a 3.65E+4n/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Inhibition of human Aurora B using H-LRRASLG as substrate after 2 hrs by HotSpot assay in presence of 33P-ATP and 10 uM ATP

Bioorg Med Chem 24: 2114-24 (2016)


Article DOI: 10.1016/j.bmc.2016.03.042
BindingDB Entry DOI: 10.7270/Q2ZW1NST
More data for this
Ligand-Target Pair