Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50293691'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50293691 (CHEMBL549469 | N-(4-(4-(5-methyl-1H-pyrazol-3-ylam...) Show SMILES CC(=O)Nc1ccc(Sc2nccc(Nc3cc(C)n[nH]3)n2)cc1 Show InChI InChI=1S/C16H16N6OS/c1-10-9-15(22-21-10)19-14-7-8-17-16(20-14)24-13-5-3-12(4-6-13)18-11(2)23/h3-9H,1-2H3,(H,18,23)(H2,17,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	207	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of Aurora-B				Bioorg Med Chem Lett 19: 3586-92 (2009) Article DOI: 10.1016/j.bmcl.2009.04.136 BindingDB Entry DOI: 10.7270/Q28K7944
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