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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50315840'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM50315840
PNG
(CHEMBL1090237 | N-(6-(pyrrolidin-1-yl)-3-styryl-1H...)
Show SMILES O=C(Cc1cccs1)Nc1cc2c(\C=C\c3ccccc3)n[nH]c2cc1N1CCCC1
Show InChI InChI=1S/C25H24N4OS/c30-25(15-19-9-6-14-31-19)26-23-16-20-21(11-10-18-7-2-1-3-8-18)27-28-22(20)17-24(23)29-12-4-5-13-29/h1-3,6-11,14,16-17H,4-5,12-13,15H2,(H,26,30)(H,27,28)/b11-10+
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S*BIO Pte. Ltd

Curated by ChEMBL


Assay Description
Inhibition of GST tagged recombinant Aurora B expressed in Hi-5 cells after 1 hr by TRF assay

Bioorg Med Chem Lett 20: 2443-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.03.018
BindingDB Entry DOI: 10.7270/Q24B31HK
More data for this
Ligand-Target Pair