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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM92869'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM92869
PNG
(4-Aminoquinazoline derivative, 6c)
Show SMILES CCN(CC)CCCOc1ccc2c(Nc3ccc(C)c(Nc4ncc(cn4)-c4cccnc4)c3)ncnc2c1
Show InChI InChI=1S/C31H34N8O/c1-4-39(5-2)14-7-15-40-26-11-12-27-29(17-26)35-21-36-30(27)37-25-10-9-22(3)28(16-25)38-31-33-19-24(20-34-31)23-8-6-13-32-18-23/h6,8-13,16-21H,4-5,7,14-15H2,1-3H3,(H,33,34,38)(H,35,36,37)
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Article
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n/an/a 202n/an/an/an/an/an/a



Southeast University



Assay Description
The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.

Chem Biol Drug Des 81: 399-407 (2013)


Article DOI: 10.1111/cbdd.12089
BindingDB Entry DOI: 10.7270/Q2Z31X71
More data for this
Ligand-Target Pair