Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM92870'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM92870 (4-Aminoquinazoline derivative, 6d) Show SMILES Cc1ccc(Nc2ncnc3cc(OCCCN4CCCC4)ccc23)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C31H32N8O/c1-22-7-8-25(16-28(22)38-31-33-19-24(20-34-31)23-6-4-11-32-18-23)37-30-27-10-9-26(17-29(27)35-21-36-30)40-15-5-14-39-12-2-3-13-39/h4,6-11,16-21H,2-3,5,12-15H2,1H3,(H,33,34,38)(H,35,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Southeast University					Assay Description The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.				Chem Biol Drug Des 81: 399-407 (2013) Article DOI: 10.1111/cbdd.12089 BindingDB Entry DOI: 10.7270/Q2Z31X71
					More data for this Ligand-Target Pair