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Found 1 hit Enz. Inhib. hit(s) with Target = 'BDNF/NT-3 growth factors receptor' and Ligand = 'BDBM50092090'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
BDNF/NT-3 growth factors receptor


(Homo sapiens (Human))		BDBM50092090
PNG
(CHEMBL3582429)
Show SMILES Fc1cccc(CNc2ccc3ncc(-c4ccc(cc4)C#N)n3n2)c1
Show InChI InChI=1S/C20H14FN5/c21-17-3-1-2-15(10-17)12-23-19-8-9-20-24-13-18(26(20)25-19)16-6-4-14(11-22)5-7-16/h1-10,13H,12H2,(H,23,25)
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Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Inhibition of Tel-fused TRKB (unknown origin) overexpressed in mouse BA/F3 cells assessed as inhibition of cell proliferation after 48 hrs by lucifer...

ACS Med Chem Lett 6: 562-7 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00050
BindingDB Entry DOI: 10.7270/Q2TM7CW4
More data for this
Ligand-Target Pair