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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM209198'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bcl-2-like protein 1


(Homo sapiens (Human))
BDBM209198
PNG
(US9266877, 144)
Show SMILES COCC1(Cn2ncc(c2C)-c2ccc(nc2C(O)=O)N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)CCCCC1
Show InChI InChI=1S/C36H38N6O4S/c1-23-27(19-37-42(23)21-36(22-46-2)16-6-3-7-17-36)25-13-14-31(39-32(25)34(44)45)41-18-15-24-9-8-10-26(28(24)20-41)33(43)40-35-38-29-11-4-5-12-30(29)47-35/h4-5,8-14,19H,3,6-7,15-18,20-22H2,1-2H3,(H,44,45)(H,38,40,43)
PDB
MMDB

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PC cid
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US Patent
<0.100<-57.1n/an/an/an/an/an/a25



ABBVIE INC.

US Patent


Assay Description
The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...


US Patent US9266877 (2016)


BindingDB Entry DOI: 10.7270/Q2H41Q7V
More data for this
Ligand-Target Pair