Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50308111 ((S,Z)-2-(5-((6-(3,4-dimethoxyphenyl)pyridin-3-yl)m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Chemical and Engineering Sciences Curated by ChEMBL | Assay Description Displacement of fluorescein-labeled Bak-BH3 peptide from human Bcl-XL by fluorescence polarization assay | J Med Chem 53: 2314-8 (2010) Article DOI: 10.1021/jm901469p BindingDB Entry DOI: 10.7270/Q2K937NJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bcl-2-like protein 1 (Homo sapiens (Human)) | BDBM50308111 ((S,Z)-2-(5-((6-(3,4-dimethoxyphenyl)pyridin-3-yl)m...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >7.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Chemical and Engineering Sciences Curated by ChEMBL | Assay Description Binding affinity to human Bcl-XL by isothermal titration calorimetry | J Med Chem 53: 2314-8 (2010) Article DOI: 10.1021/jm901469p BindingDB Entry DOI: 10.7270/Q2K937NJ | |||||||||||
More data for this Ligand-Target Pair |