BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-1 adrenergic receptor' and Ligand = 'BDBM50379086'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50379086 (CHEMBL2012521 \| CHEMBL2012522 \| LY-377604) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.0230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]Iodocyanopindolol from human adrenergic beta1 receptor expressed in insect sf9 cells by scintillation counting				ACS Med Chem Lett 2: 583-586 (2011) Article DOI: 10.1021/ml200071k BindingDB Entry DOI: 10.7270/Q20R9QDP
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50379086 (CHEMBL2012521 \| CHEMBL2012522 \| LY-377604) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.16E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human adrenergic beta1 receptor expressed in DHB-11 CHO cells assessed as cAMP accumulation after 20 mins by scintillation proxim...				ACS Med Chem Lett 2: 583-586 (2011) Article DOI: 10.1021/ml200071k BindingDB Entry DOI: 10.7270/Q20R9QDP
TBA Curated by ChEMBL					More data for this Ligand-Target Pair