BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-adrenergic receptor kinase 2' and Ligand = 'BDBM50191319'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-adrenergic receptor kinase 2


(Bos taurus)		BDBM50191319
PNG
(CHEMBL3942164)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)[C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(O)=O |r|
Show InChI InChI=1S/C76H130N22O23/c1-12-38(6)57(95-62(107)40(8)86-72(117)58(41(9)99)96-63(108)45(79)23-16-18-30-77)71(116)85-39(7)61(106)87-46(24-17-19-31-78)64(109)92-51(34-44-21-14-13-15-22-44)69(114)90-49(27-29-55(104)105)66(111)88-47(25-20-32-84-76(82)83)65(110)91-50(33-36(2)3)68(113)89-48(26-28-53(80)102)67(112)97-60(43(11)101)74(119)94-56(37(4)5)70(115)98-59(42(10)100)73(118)93-52(75(120)121)35-54(81)103/h13-15,21-22,36-43,45-52,56-60,99-101H,12,16-20,23-35,77-79H2,1-11H3,(H2,80,102)(H2,81,103)(H,85,116)(H,86,117)(H,87,106)(H,88,111)(H,89,113)(H,90,114)(H,91,110)(H,92,109)(H,93,118)(H,94,119)(H,95,107)(H,96,108)(H,97,112)(H,98,115)(H,104,105)(H,120,121)(H4,82,83,84)/t38-,39-,40-,41+,42+,43+,45-,46-,47-,48-,49-,50-,51-,52-,56-,57-,58-,59-,60-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.16E+4n/an/an/an/an/an/a



Universit£ degli Studi di Messina

Curated by ChEMBL


Assay Description
Inhibition of recombinant bovine GRK3 expressed in Sf9 insect cells assessed as decrease in phosphorylation of urea-washed bovine rod outer segments ...

J Med Chem 59: 9277-9294 (2016)


BindingDB Entry DOI: 10.7270/Q2348NB9
More data for this
Ligand-Target Pair