BindingDB PrimarySearch

Found 48 hits Enz. Inhib. hit(s) with Target = 'Beta-lactamase' and Ligand = 'BDBM50021959'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-lactamase (Mycobacterium tuberculosis H37Rv)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
Indian Institute of Technology					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in sodium phosphate buffer (50 mM, pH 7.2) and a 1 cm pathlengt...				Biochemistry 54: 5657-64 (2015) Article DOI: 10.1021/acs.biochem.5b00698 BindingDB Entry DOI: 10.7270/Q29W0D7G
Indian Institute of Technology					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description Inhibition of Klebsiella pneumoniae 1534 beta-lactamase KPC-2 by competitive assay				Antimicrob Agents Chemother 54: 2867-77 (2010) Article DOI: 10.1128/AAC.00197-10 BindingDB Entry DOI: 10.7270/Q2QJ7HJP
Case Western Reserve University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Citrobacter freundii beta-lactamase SHV-95				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	2.27E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Acinetobacter baumannii beta-lactamase SHV-48				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter gillenii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
H�pital de Bic�tre Curated by ChEMBL					Assay Description Inhibition of Citrobacter gillenii CIP 106783 Beta-lactamase GIL1 expressed in Escherichia coli DH10B				Antimicrob Agents Chemother 51: 1365-72 (2007) Article DOI: 10.1128/AAC.01152-06 BindingDB Entry DOI: 10.7270/Q2S46SS7
H�pital de Bic�tre Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Escherichia coli CTX-M-15				Antimicrob Agents Chemother 51: 3089-95 (2007) Article DOI: 10.1128/AAC.00218-07 BindingDB Entry DOI: 10.7270/Q2BG2NR1
					More data for this Ligand-Target Pair
Beta-lactamase (Salmonella enterica subsp. enterica serovar Westha...)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre National de R£f£rence des Salmonella Curated by ChEMBL					Assay Description Inhibition of Salmonella enterica serotype Westhampton beta-lactamase CTX-M-53				Antimicrob Agents Chemother 53: 1944-51 (2009) Article DOI: 10.1128/AAC.01581-08 BindingDB Entry DOI: 10.7270/Q2445MRF
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against Escherichia coli TEM-3 Beta-lactamase				J Med Chem 41: 3961-71 (1998) Article DOI: 10.1021/jm980023c BindingDB Entry DOI: 10.7270/Q2HT2NF0
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Klebsiella pneumoniae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-55				Antimicrob Agents Chemother 52: 1897-8 (2008) Article DOI: 10.1128/AAC.01525-07 BindingDB Entry DOI: 10.7270/Q2PV6KKC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Klebsiella oxytoca)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	30.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Klebsiella oxytoca HC7 Class-IV K1 type beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas luteola)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Institut Pasteur Curated by ChEMBL					Assay Description Inhibition of Pseudomonas luteola LAM Beta-lactamase LUT-1				Antimicrob Agents Chemother 54: 45-51 (2010) Article DOI: 10.1128/AAC.00427-09 BindingDB Entry DOI: 10.7270/Q2KS6VCC
Institut Pasteur Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Proteus mirabilis)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	65.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Proteus vulgaris HJ33C Class-I beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Institut Pasteur Hellenique Curated by ChEMBL					Assay Description Inhibition of Escherichia coli beta-lactamase SCO1				Antimicrob Agents Chemother 51: 2185-8 (2007) Article DOI: 10.1128/AAC.01439-06 BindingDB Entry DOI: 10.7270/Q2028SFP
Institut Pasteur Hellenique Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against Penicillinase from Staphylococcus aureus TH-14 using piperacillin (40 uM) as a substrate				J Med Chem 30: 1469-74 (1987) BindingDB Entry DOI: 10.7270/Q28G8JQ0
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Proteus mirabilis)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	95.4	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Proteus mirabilis C889 beta-lactamase assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate assay				J Nat Prod 57: 654-7 (1994) Article DOI: 10.1021/np50107a016 BindingDB Entry DOI: 10.7270/Q2SQ935W
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
H�pital de Bic�tre Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa 531 beta-lactamase BEL-2				Antimicrob Agents Chemother 54: 533-5 (2010) Article DOI: 10.1128/AAC.00859-09 BindingDB Entry DOI: 10.7270/Q2G163PS
H�pital de Bic�tre Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
H�pital de Bic�tre Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa 51170 beta-lactamase BEL-1				Antimicrob Agents Chemother 54: 533-5 (2010) Article DOI: 10.1128/AAC.00859-09 BindingDB Entry DOI: 10.7270/Q2G163PS
H�pital de Bic�tre Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Hellenic Pasteur Institute Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa GES-13 beta lactamase				Antimicrob Agents Chemother 54: 1331-3 (2010) Article DOI: 10.1128/AAC.01561-09 BindingDB Entry DOI: 10.7270/Q29C6XN5
Hellenic Pasteur Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus Russell beta-lactamase assessed as inhibition of nitrocefin hydrolysis pre-incubated for 5 mins by microtiter pla...				J Nat Prod 57: 654-7 (1994) Article DOI: 10.1021/np50107a016 BindingDB Entry DOI: 10.7270/Q2SQ935W
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					Assay Description Deacylation of 18SH Beta-lactamase of Pseudomonas aeruginosa				J Med Chem 41: 3961-71 (1998) Article DOI: 10.1021/jm980023c BindingDB Entry DOI: 10.7270/Q2HT2NF0
F. Hoffmann-La Roche Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Klebsiella pneumoniae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Health Dr. Ricardo Jorge Av. Padre Cruz Curated by ChEMBL					Assay Description Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-72				Antimicrob Agents Chemother 52: 1806-11 (2008) Article DOI: 10.1128/AAC.01381-07 BindingDB Entry DOI: 10.7270/Q2TM7B93
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
CHU Clermont-Ferrand Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DH5alpha beta-lactamase TEM-158				Antimicrob Agents Chemother 51: 4181-3 (2007) Article DOI: 10.1128/AAC.00614-07 BindingDB Entry DOI: 10.7270/Q2H131TX
CHU Clermont-Ferrand Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Citrobacter freundii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Citrobacter freundii 87470 Class-I beta-lactamase enzyme				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against beta-Lactamase enzyme derived from Enterobacter cloacae SC 12368 E-2				Bioorg Med Chem Lett 5: 1513-1518 (1995) Article DOI: 10.1016/0960-894X(95)00249-S BindingDB Entry DOI: 10.7270/Q2ZW1MDG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against beta-Lactamase enzyme derived from Enterobacter cloacae P99				Bioorg Med Chem Lett 5: 1513-1518 (1995) Article DOI: 10.1016/0960-894X(95)00249-S BindingDB Entry DOI: 10.7270/Q2ZW1MDG
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitory activity against Enterobacter cloacae HC8 Class-I beta-lactamase enzyme type P99				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZW1P2T
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Serratia fonticola)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Aveiro Curated by ChEMBL					Assay Description Inhibition of Serratia fonticola UTAD54 SFC1 beta lactamase expressed in Escherichia coli BL21(DE3) by SDS-PAGE				Antimicrob Agents Chemother 51: 4512-4 (2007) Article DOI: 10.1128/AAC.00491-07 BindingDB Entry DOI: 10.7270/Q2PK0FX5
University of Aveiro Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	7.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for its inhibitory activity against Escherichia coli K12(PSE4) class A beta-lactamase				Citation and Details Article DOI: 10.1016/S0960-894X(01)80506-0 BindingDB Entry DOI: 10.7270/Q21V5HPM
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Proteus mirabilis)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	9.54E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for its inhibitory activity against Proteus mirabilis C889 class A beta-lactamase				Citation and Details Article DOI: 10.1016/S0960-894X(01)80506-0 BindingDB Entry DOI: 10.7270/Q21V5HPM
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for beta-lactamase inhibition activity of Enterobacter cloacae after 15 min of preincubation with the enzyme at 37 degree C				Bioorg Med Chem Lett 7: 2217-2222 (1997) Article DOI: 10.1016/S0960-894X(97)00401-0 BindingDB Entry DOI: 10.7270/Q2M32VR6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novexel SA Curated by ChEMBL					Assay Description Inhibition of Enterobacter cloacae beta-lactamase P99 assessed as nitrocefin hydrolysis after 5 mins enzyme-compound preincubation				Antimicrob Agents Chemother 54: 5132-8 (2010) Article DOI: 10.1128/AAC.00568-10 BindingDB Entry DOI: 10.7270/Q2CJ8DSV
Novexel SA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lek d.d. Curated by ChEMBL					Assay Description The compound was tested for its inhibitory activity towards Class C beta-lactamase from Enterobacter cloacae 908R at 0.8 umol concentration				Bioorg Med Chem Lett 12: 971-5 (2002) BindingDB Entry DOI: 10.7270/Q2NC61S9
Lek d.d. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novexel SA Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa beta-lactamase AmpC assessed as nitrocefin hydrolysis after 5 mins enzyme-compound preincubation				Antimicrob Agents Chemother 54: 5132-8 (2010) Article DOI: 10.1128/AAC.00568-10 BindingDB Entry DOI: 10.7270/Q2CJ8DSV
Novexel SA Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lek Pharmaceuticals d.d. Curated by ChEMBL					Assay Description Inhibition of Enterobacter cloacae AmpC				J Med Chem 50: 4113-21 (2007) Article DOI: 10.1021/jm0703237 BindingDB Entry DOI: 10.7270/Q2FF3T5F
Lek Pharmaceuticals d.d. Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	7.0	37
NABRIVA THERAPEUTICS AG US Patent					Assay Description The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...				US Patent US9120808 (2015) BindingDB Entry DOI: 10.7270/Q2Q81BT5
NABRIVA THERAPEUTICS AG US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Staphylococcus aureus)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for its inhibitory activity against Staphylococcus aureus Russel class A beta-lactamase				Citation and Details Article DOI: 10.1016/S0960-894X(01)80506-0 BindingDB Entry DOI: 10.7270/Q21V5HPM
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter genomosp. 3)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.36E+5	n/a	n/a	n/a	n/a	n/a	n/a
Complejo Hospitalario Universitario Juan Canalejo-INIBIC Curated by ChEMBL					Assay Description Inhibition of Acinetobacter genomosp. 3 isolate 65 ADC-14				Antimicrob Agents Chemother 53: 1177-84 (2009) Article DOI: 10.1128/AAC.00485-08 BindingDB Entry DOI: 10.7270/Q2CN7454
					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of Escherichia coli beta-lactamase ACC4				Antimicrob Agents Chemother 51: 3763-7 (2007) Article DOI: 10.1128/AAC.00389-07 BindingDB Entry DOI: 10.7270/Q2222THB
Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.78E+5	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Enterobacter cloacae P99 beta-lactamase assessed as inhibition of nitrocefin hydrolysis pre-incubated for 5 mins by microtiter plate as...				J Nat Prod 57: 654-7 (1994) Article DOI: 10.1021/np50107a016 BindingDB Entry DOI: 10.7270/Q2SQ935W
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Aventis pharma Curated by ChEMBL					Assay Description Inhibition of hydrolysis of nitrocephin after 5 min pre-incubation with P99 beta-lactamases (class C)				Bioorg Med Chem Lett 14: 2489-92 (2004) Article DOI: 10.1016/j.bmcl.2004.03.004 BindingDB Entry DOI: 10.7270/Q2W37WWS
Aventis pharma Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter genomosp. 3)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.46E+6	n/a	n/a	n/a	n/a	n/a	n/a
Complejo Hospitalario Universitario Juan Canalejo-INIBIC Curated by ChEMBL					Assay Description Inhibition of Acinetobacter genomosp. 3 isolate 103 ADC-16				Antimicrob Agents Chemother 53: 1177-84 (2009) Article DOI: 10.1128/AAC.00485-08 BindingDB Entry DOI: 10.7270/Q2CN7454
					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity to Acinetobacter baumannii ADC-33 beta-lactamase				Antimicrob Agents Chemother 54: 3484-8 (2010) Article DOI: 10.1128/AAC.00050-10 BindingDB Entry DOI: 10.7270/Q2348KM2
INSERM Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter genomosp. 3)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.93E+6	n/a	n/a	n/a	n/a	n/a	n/a
Complejo Hospitalario Universitario Juan Canalejo-INIBIC Curated by ChEMBL					Assay Description Inhibition of Acinetobacter genomosp. 3 isolate 195 ADC-18				Antimicrob Agents Chemother 53: 1177-84 (2009) Article DOI: 10.1128/AAC.00485-08 BindingDB Entry DOI: 10.7270/Q2CN7454
					More data for this Ligand-Target Pair
Beta-lactamase (Acinetobacter baumannii)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+6	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity to Acinetobacter baumannii ADC-11 beta-lactamase				Antimicrob Agents Chemother 54: 3484-8 (2010) Article DOI: 10.1128/AAC.00050-10 BindingDB Entry DOI: 10.7270/Q2348KM2
INSERM Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.71E+6	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa A beta-lactamase assessed as inhibition of nitrocefin hydrolysis preincubated for 5 mins by microtiter plate ass...				J Nat Prod 57: 654-7 (1994) Article DOI: 10.1021/np50107a016 BindingDB Entry DOI: 10.7270/Q2SQ935W
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Enterobacter cloacae)	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	8.03E+8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for its inhibitory activity against Enterobacter cloacae P99 class C beta-lactamase				Citation and Details Article DOI: 10.1016/S0960-894X(01)80506-0 BindingDB Entry DOI: 10.7270/Q21V5HPM
TBA					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	2.15E+9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Concentration required for its inhibitory activity against Pseudomonas aeruginosa class C beta-lactamase				Citation and Details Article DOI: 10.1016/S0960-894X(01)80506-0 BindingDB Entry DOI: 10.7270/Q21V5HPM
TBA					More data for this Ligand-Target Pair