Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136799 (US8865911, 48 Isomer 1 | US8865911, 48 Isomer 3 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | 9.2 | n/a |
Astrazeneca AB US Patent | Assay Description TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA... | US Patent US8865911 (2014) BindingDB Entry DOI: 10.7270/Q2T72G4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136799 (US8865911, 48 Isomer 1 | US8865911, 48 Isomer 3 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.57E+3 | n/a | n/a | n/a | n/a | 9.2 | n/a |
Astrazeneca AB US Patent | Assay Description The beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA 460) was clo... | US Patent US8865911 (2014) BindingDB Entry DOI: 10.7270/Q2T72G4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136799 (US8865911, 48 Isomer 1 | US8865911, 48 Isomer 3 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.04E+3 | n/a | n/a | n/a | n/a | 9.2 | n/a |
Astrazeneca AB US Patent | Assay Description The beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA 460) was clo... | US Patent US8865911 (2014) BindingDB Entry DOI: 10.7270/Q2T72G4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136799 (US8865911, 48 Isomer 1 | US8865911, 48 Isomer 3 | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.57E+4 | n/a | n/a | n/a | n/a | 9.2 | n/a |
Astrazeneca AB US Patent | Assay Description The beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA 460) was clo... | US Patent US8865911 (2014) BindingDB Entry DOI: 10.7270/Q2T72G4T | |||||||||||
More data for this Ligand-Target Pair |