Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50137697 ((S)-2-Ethyl-4-(S)-hydroxy-5-[(S)-2-((S)-2-hydroxy-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity against Beta-secretase 1 in human HEK293 cells | Bioorg Med Chem Lett 14: 245-50 (2003) BindingDB Entry DOI: 10.7270/Q2H41S0J | |||||||||||
More data for this Ligand-Target Pair |