Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50171339 (1-(3-Acetyl-phenyl)-3-(3-ethylsulfanyl-[1,2,4]thia...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 2.88E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zürich Curated by ChEMBL | Assay Description Predicted binding affinity for beta secretase by linear interaction energy continuum electrostatics | J Med Chem 48: 5108-11 (2005) Article DOI: 10.1021/jm050499d BindingDB Entry DOI: 10.7270/Q228074P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50171339 (1-(3-Acetyl-phenyl)-3-(3-ethylsulfanyl-[1,2,4]thia...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >25 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Zürich Curated by ChEMBL | Assay Description Inhibitory concentration against beta-site APP cleaving enzyme (BACE-1) by fluorescence resonance energy transfer assay | J Med Chem 48: 5108-11 (2005) Article DOI: 10.1021/jm050499d BindingDB Entry DOI: 10.7270/Q228074P | |||||||||||
More data for this Ligand-Target Pair |