Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50182871 (CHEMBL381826 | N-((2S,5S)-5-((S)-1-((1R,2S)-1-(3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of BACE1 | Bioorg Med Chem Lett 16: 2380-6 (2006) Article DOI: 10.1016/j.bmcl.2006.01.108 BindingDB Entry DOI: 10.7270/Q2TD9WXG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50182871 (CHEMBL381826 | N-((2S,5S)-5-((S)-1-((1R,2S)-1-(3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human BACE1 by FRET assay | Bioorg Med Chem 18: 3175-86 (2010) Article DOI: 10.1016/j.bmc.2010.03.032 BindingDB Entry DOI: 10.7270/Q26M36ZV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50182871 (CHEMBL381826 | N-((2S,5S)-5-((S)-1-((1R,2S)-1-(3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human recombinant BACE1 by FRET assay | Bioorg Med Chem Lett 18: 1643-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.056 BindingDB Entry DOI: 10.7270/Q2J38S96 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50182871 (CHEMBL381826 | N-((2S,5S)-5-((S)-1-((1R,2S)-1-(3-(...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human recombinant BACE1 | Bioorg Med Chem Lett 16: 4354-9 (2006) Article DOI: 10.1016/j.bmcl.2006.05.046 BindingDB Entry DOI: 10.7270/Q26M36F4 | |||||||||||
More data for this Ligand-Target Pair |