Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 1' and Ligand = 'BDBM50299242'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50299242 (3-(3H-Imidazo[4,5-c]pyridin-2-yl)-5H-dibenzo[b,e][...) Show SMILES O=C(Nc1nc2ccncc2[nH]1)c1ccc2c(Nc3ccccc3NC2=O)c1 Show InChI InChI=1S/C20H14N6O2/c27-18(26-20-24-15-7-8-21-10-17(15)25-20)11-5-6-12-16(9-11)22-13-3-1-2-4-14(13)23-19(12)28/h1-10,22H,(H,23,28)(H2,24,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of human recombinant BACE1 by FRET assay				J Med Chem 52: 6484-8 (2009) Article DOI: 10.1021/jm9008482 BindingDB Entry DOI: 10.7270/Q2765FC2
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