Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM123860'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 2 (Homo sapiens (Human))	BDBM123860 (US8748418, 4) Show SMILES C[C@@]1(N=C(N)COC[C@@H]1F)c1cc(NC2CCCOC2)ccc1F |r,t:2| Show InChI InChI=1S/C17H23F2N3O2/c1-17(15(19)9-24-10-16(20)22-17)13-7-11(4-5-14(13)18)21-12-3-2-6-23-8-12/h4-5,7,12,15,21H,2-3,6,8-10H2,1H3,(H2,20,22)/t12?,15-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	4.5	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...				US Patent US8748418 (2014) BindingDB Entry DOI: 10.7270/Q2C53JJP
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