Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Beta-secretase 2' and Ligand = 'BDBM50358939'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 2 (Homo sapiens (Human))	BDBM50358939 (CHEMBL1923708) Show SMILES COc1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1nc2ccccn2c1NC(C)(C)C Show InChI InChI=1S/C25H25N5O/c1-25(2,3)29-24-22(28-21-7-5-6-14-30(21)24)16-8-10-17(11-9-16)23-26-19-13-12-18(31-4)15-20(19)27-23/h5-15,29H,1-4H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis menton equation				J Med Chem 54: 8373-85 (2011) Checked by Author Article DOI: 10.1021/jm201181f BindingDB Entry DOI: 10.7270/Q279453T
					More data for this Ligand-Target Pair
Beta-secretase 2 (Homo sapiens (Human))	BDBM50358939 (CHEMBL1923708) Show SMILES COc1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1nc2ccccn2c1NC(C)(C)C Show InChI InChI=1S/C25H25N5O/c1-25(2,3)29-24-22(28-21-7-5-6-14-30(21)24)16-8-10-17(11-9-16)23-26-19-13-12-18(31-4)15-20(19)27-23/h5-15,29H,1-4H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Sharjah Curated by ChEMBL					Assay Description Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysis				J Med Chem 54: 8373-85 (2011) Checked by Author Article DOI: 10.1021/jm201181f BindingDB Entry DOI: 10.7270/Q279453T
					More data for this Ligand-Target Pair