Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50265662'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50265662 (CHEMBL4078875) Show SMILES CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1Oc1ccccc1 Show InChI InChI=1S/C22H24N2O5S/c1-4-28-21-14-22(25)24(3)15-19(21)18-13-16(23-30(26,27)5-2)11-12-20(18)29-17-9-7-6-8-10-17/h6-15,23H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...				J Med Chem 60: 3828-3850 (2017) Article DOI: 10.1021/acs.jmedchem.7b00017 BindingDB Entry DOI: 10.7270/Q2BR8VPN
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50265662 (CHEMBL4078875) Show SMILES CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1Oc1ccccc1 Show InChI InChI=1S/C22H24N2O5S/c1-4-28-21-14-22(25)24(3)15-19(21)18-13-16(23-30(26,27)5-2)11-12-20(18)29-17-9-7-6-8-10-17/h6-15,23H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
AbbVie Inc. Curated by ChEMBL					Assay Description Inhibition of BRD4 in human NCI-H1299 cells after 24 hrs by Bright-Glo luciferase reporter gene assay				J Med Chem 60: 3828-3850 (2017) Article DOI: 10.1021/acs.jmedchem.7b00017 BindingDB Entry DOI: 10.7270/Q2BR8VPN
					More data for this Ligand-Target Pair