Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4' and Ligand = 'BDBM50380675'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50380675 (CHEMBL2017281) Show SMILES COc1cc2c(Nc3cccc4cccnc34)c(cnc2cc1-c1c(C)noc1C)C(N)=O |(39.67,-12.44,;39.67,-13.98,;41,-14.75,;42.33,-13.98,;43.67,-14.75,;44.99,-13.97,;44.98,-12.43,;43.65,-11.67,;42.33,-12.45,;40.99,-11.7,;40.98,-10.15,;42.31,-9.37,;42.3,-7.85,;43.62,-7.07,;44.96,-7.83,;44.97,-9.37,;43.64,-10.14,;46.33,-14.73,;46.34,-16.28,;45,-17.06,;43.67,-16.29,;42.33,-17.07,;41,-16.3,;39.67,-17.07,;39.63,-18.61,;40.86,-19.54,;38.16,-19.06,;37.28,-17.79,;38.21,-16.56,;37.76,-15.09,;47.66,-13.96,;49,-14.72,;47.65,-12.42,)| Show InChI InChI=1S/C25H21N5O3/c1-13-22(14(2)33-30-13)17-10-20-16(11-21(17)32-3)24(18(12-28-20)25(26)31)29-19-8-4-6-15-7-5-9-27-23(15)19/h4-12H,1-3H3,(H2,26,31)(H,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to BRD4 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysis				Bioorg Med Chem Lett 22: 2968-72 (2012) Article DOI: 10.1016/j.bmcl.2012.02.041 BindingDB Entry DOI: 10.7270/Q2JS9RKN
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