BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50325723'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50325723 ((R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of CCL3-induced chemotaxis after 3 hrs				Bioorg Med Chem Lett 20: 5477-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.082 BindingDB Entry DOI: 10.7270/Q2319W3D
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50325723 ((R)-2-(4-(4-chlorobenzyl)-5-methyl-4H-1,2,4-triazo...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-MIP1alpha from human recombinant CCR1 expressed in HEK293 cells after 4 hrs by SPA				Bioorg Med Chem Lett 20: 5477-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.082 BindingDB Entry DOI: 10.7270/Q2319W3D
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair