Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 1' and Ligand = 'BDBM50435687'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50435687 (CHEMBL2391939) Show SMILES O[C@H](COc1cc(F)ccc1C(=O)NC1CC1)CN1CCC2(Cc3cc(Cl)ccc3O2)CC1 |r| Show InChI InChI=1S/C25H28ClFN2O4/c26-17-1-6-22-16(11-17)13-25(33-22)7-9-29(10-8-25)14-20(30)15-32-23-12-18(27)2-5-21(23)24(31)28-19-3-4-19/h1-2,5-6,11-12,19-20,30H,3-4,7-10,13-15H2,(H,28,31)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of MIP-1alpha-induced chemotaxis after 2 hrs by fluorescence assay				Bioorg Med Chem Lett 23: 3500-4 (2013) Article DOI: 10.1016/j.bmcl.2013.04.047 BindingDB Entry DOI: 10.7270/Q2FJ2J5S
					More data for this Ligand-Target Pair