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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 10' and Ligand = 'BDBM50199089'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 10


(Homo sapiens (Human))		BDBM50199089
PNG
(CHEMBL3928968)
Show SMILES Nc1c(Cl)cc(cc1Cl)S(=O)(=O)NC(CCn1cccc1C#N)C(=O)N1CCCC1
Show InChI InChI=1S/C19H21Cl2N5O3S/c20-15-10-14(11-16(21)18(15)23)30(28,29)24-17(19(27)26-6-1-2-7-26)5-9-25-8-3-4-13(25)12-22/h3-4,8,10-11,17,24H,1-2,5-7,9,23H2
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Similars
Article
PubMed
n/an/a<1.00E+4n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR10 expressed in CHOK1 cells coexpressing aequorin/Galphaq assessed as inhibition of human CCL27-dependent calcium flu...

Bioorg Med Chem Lett 26: 5277-5283 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.047
BindingDB Entry DOI: 10.7270/Q2KD20WF
More data for this
Ligand-Target Pair