Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50197993'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50197993 ((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6]-[#8]-c1cc(nn1-c1ccc2ccccc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C29H30Cl2N6O4/c1-40-28(39)24(7-4-11-34-29(32)33)35-26(38)10-12-41-27-17-25(20-13-21(30)16-22(31)14-20)36-37(27)23-9-8-18-5-2-3-6-19(18)15-23/h2-3,5-6,8-9,13-17,24H,4,7,10-12H2,1H3,(H,35,38)(H4,32,33,34)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61.9	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of CCR2				Eur J Med Chem 45: 3394-406 (2010) Article DOI: 10.1016/j.ejmech.2010.04.024 BindingDB Entry DOI: 10.7270/Q2JQ1275
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50197993 ((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6]-[#8]-c1cc(nn1-c1ccc2ccccc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C29H30Cl2N6O4/c1-40-28(39)24(7-4-11-34-29(32)33)35-26(38)10-12-41-27-17-25(20-13-21(30)16-22(31)14-20)36-37(27)23-9-8-18-5-2-3-6-19(18)15-23/h2-3,5-6,8-9,13-17,24H,4,7,10-12H2,1H3,(H,35,38)(H4,32,33,34)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-hMCP1 from CCR2 expressed in human peripheral blood monocytes after 60 mins				Bioorg Med Chem Lett 17: 807-13 (2007) Article DOI: 10.1016/j.bmcl.2006.10.060 BindingDB Entry DOI: 10.7270/Q2P84BJD
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50197993 ((S)-2-{3-[5-(3,5-dichloro-phenyl)-2-naphthalen-2-y...) Show SMILES [#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#6]-[#8]-c1cc(nn1-c1ccc2ccccc2c1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C29H30Cl2N6O4/c1-40-28(39)24(7-4-11-34-29(32)33)35-26(38)10-12-41-27-17-25(20-13-21(30)16-22(31)14-20)36-37(27)23-9-8-18-5-2-3-6-19(18)15-23/h2-3,5-6,8-9,13-17,24H,4,7,10-12H2,1H3,(H,35,38)(H4,32,33,34)/t24-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity against human CCR2 receptor assessed as inhibition of MCP1-induced migration of human peripheral blood monocytes				Bioorg Med Chem Lett 17: 807-13 (2007) Article DOI: 10.1016/j.bmcl.2006.10.060 BindingDB Entry DOI: 10.7270/Q2P84BJD
					More data for this Ligand-Target Pair