BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50257994'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assay				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assay				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in CHO cells by chemotaxis assay				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]hMCP1 from human CCR2 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 1830-4 (2009) Article DOI: 10.1016/j.bmcl.2008.12.050 BindingDB Entry DOI: 10.7270/Q2GH9HVZ
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50257994 ((1S,3R)-N-(3,5-bis(-trifluoromethyl)benzyl)-1-iso ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	239	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at CCR2 (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-010-9501-4 BindingDB Entry DOI: 10.7270/Q20R9S95
TBA					More data for this Ligand-Target Pair