Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50142444'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50142444 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C Show InChI InChI=1S/C25H32FN7O/c1-18-13-21(24-29-30-31-32(24)2)16-23(14-18)28-25(34)27-10-4-12-33-11-3-5-20(17-33)15-19-6-8-22(26)9-7-19/h6-9,13-14,16,20H,3-5,10-12,15,17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxis				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50142444 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C Show InChI InChI=1S/C25H32FN7O/c1-18-13-21(24-29-30-31-32(24)2)16-23(14-18)28-25(34)27-10-4-12-33-11-3-5-20(17-33)15-19-6-8-22(26)9-7-19/h6-9,13-14,16,20H,3-5,10-12,15,17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]-eotaxin.				Bioorg Med Chem Lett 14: 1645-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.059 BindingDB Entry DOI: 10.7270/Q2RB741N
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50142444 (1-(3-((S)-3-(4-fluorobenzyl)piperidin-1-yl)propyl)...) Show SMILES Cc1cc(NC(=O)NCCCN2CCC[C@@H](Cc3ccc(F)cc3)C2)cc(c1)-c1nnnn1C Show InChI InChI=1S/C25H32FN7O/c1-18-13-21(24-29-30-31-32(24)2)16-23(14-18)28-25(34)27-10-4-12-33-11-3-5-20(17-33)15-19-6-8-22(26)9-7-19/h6-9,13-14,16,20H,3-5,10-12,15,17H2,1-2H3,(H2,27,28,34)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 576-85 (2008) Article DOI: 10.1016/j.bmcl.2007.11.067 BindingDB Entry DOI: 10.7270/Q2057GS3
					More data for this Ligand-Target Pair