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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 3' and Ligand = 'BDBM50372836'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50372836
PNG
(CHEMBL402331)
Show SMILES CNC(=O)O[C@H](C[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)N1CCC[C@@H](Cc2ccc(F)cc2)C1
Show InChI InChI=1S/C27H35FN8O3/c1-18(30-26(37)31-23-8-4-7-21(16-23)25-32-33-34-35(25)3)14-24(39-27(38)29-2)36-13-5-6-20(17-36)15-19-9-11-22(28)12-10-19/h4,7-12,16,18,20,24H,5-6,13-15,17H2,1-3H3,(H,29,38)(H2,30,31,37)/t18-,20+,24-/m1/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Displacement of [125I]eotaxin from human CCR3 receptor expressed in CHO cells


Bioorg Med Chem Lett 18: 576-85 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.067
BindingDB Entry DOI: 10.7270/Q2057GS3
More data for this
Ligand-Target Pair
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50372836
PNG
(CHEMBL402331)
Show SMILES CNC(=O)O[C@H](C[C@@H](C)NC(=O)Nc1cccc(c1)-c1nnnn1C)N1CCC[C@@H](Cc2ccc(F)cc2)C1
Show InChI InChI=1S/C27H35FN8O3/c1-18(30-26(37)31-23-8-4-7-21(16-23)25-32-33-34-35(25)3)14-24(39-27(38)29-2)36-13-5-6-20(17-36)15-19-9-11-22(28)12-10-19/h4,7-12,16,18,20,24H,5-6,13-15,17H2,1-3H3,(H,29,38)(H2,30,31,37)/t18-,20+,24-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.870n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Antagonist activity at human CCR3 receptor in human eosinophil assessed as inhibition of eotaxin-induced chemotaxis


Bioorg Med Chem Lett 18: 576-85 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.067
BindingDB Entry DOI: 10.7270/Q2057GS3
More data for this
Ligand-Target Pair