Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 8' and Ligand = 'BDBM50203868'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50203868 (CHEMBL412116 | N-[4-(4-methoxy-phenylsulfamoyl)-na...) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)c3ccccc23)cc1 Show InChI InChI=1S/C24H20N2O4S/c1-30-19-13-11-18(12-14-19)26-31(28,29)23-16-15-22(20-9-5-6-10-21(20)23)25-24(27)17-7-3-2-4-8-17/h2-16,26H,1H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assay				J Med Chem 50: 566-84 (2007) Article DOI: 10.1021/jm061118e BindingDB Entry DOI: 10.7270/Q24J0DSN
					More data for this Ligand-Target Pair
C-C chemokine receptor type 8 (Homo sapiens (Human))	BDBM50203868 (CHEMBL412116 | N-[4-(4-methoxy-phenylsulfamoyl)-na...) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3)c3ccccc23)cc1 Show InChI InChI=1S/C24H20N2O4S/c1-30-19-13-11-18(12-14-19)26-31(28,29)23-16-15-22(20-9-5-6-10-21(20)23)25-24(27)17-7-3-2-4-8-17/h2-16,26H,1H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...				J Med Chem 50: 566-84 (2007) Article DOI: 10.1021/jm061118e BindingDB Entry DOI: 10.7270/Q24J0DSN
					More data for this Ligand-Target Pair