Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM50236295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236295 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(m...) Show SMILES CNS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O3S/c1-23-29(27,28)25-19(26)4-2-3-16-17-11-13(12-22)5-10-18(17)24-20(16)14-6-8-15(21)9-7-14/h5-11,23-24H,2-4H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50236295 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(m...) Show SMILES CNS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O3S/c1-23-29(27,28)25-19(26)4-2-3-16-17-11-13(12-22)5-10-18(17)24-20(16)14-6-8-15(21)9-7-14/h5-11,23-24H,2-4H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Oryctolagus cuniculus)	BDBM50236295 (4-[5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl]-N-[(m...) Show SMILES CNS(=O)(=O)NC(=O)CCCc1c([nH]c2ccc(cc12)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C20H19FN4O3S/c1-23-29(27,28)25-19(26)4-2-3-16-17-11-13(12-22)5-10-18(17)24-20(16)14-6-8-15(21)9-7-14/h5-11,23-24H,2-4H2,1H3,(H,25,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at rabbit CXCR2 by neutrophil chemotaxis assay				Bioorg Med Chem Lett 18: 1926-30 (2008) Article DOI: 10.1016/j.bmcl.2008.01.127 BindingDB Entry DOI: 10.7270/Q20P10V3
					More data for this Ligand-Target Pair