Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'C-X-C chemokine receptor type 2' and Ligand = 'BDBM50302105'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50302105 (3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-di...) Show SMILES CCN(Cc1ccc(F)cc1)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O Show InChI InChI=1S/C22H23FN4O4/c1-4-27(12-13-8-10-14(23)11-9-13)25-18-17(20(29)21(18)30)24-16-7-5-6-15(19(16)28)22(31)26(2)3/h5-11,24-25,28H,4,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
WuXi PharmaTech Co. Ltd Curated by ChEMBL					Assay Description Displacement of [125I]IL-8 from human CXCR2 expressed in mouse BaF3 cells by liquid scintillation counting				Bioorg Med Chem Lett 19: 5741-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.014 BindingDB Entry DOI: 10.7270/Q25H7GB8
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50302105 (3-(2-(2-ethyl-2-(4-fluorobenzyl)hydrazinyl)-3,4-di...) Show SMILES CCN(Cc1ccc(F)cc1)Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O Show InChI InChI=1S/C22H23FN4O4/c1-4-27(12-13-8-10-14(23)11-9-13)25-18-17(20(29)21(18)30)24-16-7-5-6-15(19(16)28)22(31)26(2)3/h5-11,24-25,28H,4,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
WuXi PharmaTech Co. Ltd Curated by ChEMBL					Assay Description Antagonist activity at CXCR2 expressed in CHO cells assessed as inhibition of IL-8-induced chemotaxis				Bioorg Med Chem Lett 19: 5741-5 (2009) Article DOI: 10.1016/j.bmcl.2009.08.014 BindingDB Entry DOI: 10.7270/Q25H7GB8
					More data for this Ligand-Target Pair