Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human)) | BDBM50322649 ((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation counting | J Med Chem 53: 4938-48 (2010) Article DOI: 10.1021/jm1003705 BindingDB Entry DOI: 10.7270/Q2QR4X9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human)) | BDBM50322649 ((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Displacement of [125I-C3a] from C3a receptor in human PBMC by scintillation counting | J Med Chem 53: 4938-48 (2010) Article DOI: 10.1021/jm1003705 BindingDB Entry DOI: 10.7270/Q2QR4X9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human)) | BDBM50322649 ((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Agonist activity at C3aR in human MDM cells assessed as Ca2+ response | Bioorg Med Chem Lett 25: 5604-8 (2015) Article DOI: 10.1016/j.bmcl.2015.10.038 BindingDB Entry DOI: 10.7270/Q2Q2437Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human)) | BDBM50322649 ((2S,5S,8S,11S,14S,17S)-17-amino-2-(3-guanidinoprop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 320 | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Agonist activity at human C3a receptor in human U937 cells assessed as induction of intracellular calcium release | J Med Chem 53: 4938-48 (2010) Article DOI: 10.1021/jm1003705 BindingDB Entry DOI: 10.7270/Q2QR4X9F | |||||||||||
More data for this Ligand-Target Pair |