BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'C3a anaphylatoxin chemotactic receptor' and Ligand = 'BDBM50422988'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Displacement of [125I]-C3a from C3AR in HMDMs by scintillation counting method				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
UCB Global Chemistry Curated by ChEMBL					Assay Description Inhibition of human C3a receptor expressed on HMC1 cells by SPA assay				Bioorg Med Chem Lett 17: 3258-61 (2007) Article DOI: 10.1016/j.bmcl.2007.04.022 BindingDB Entry DOI: 10.7270/Q2V69KTN
UCB Global Chemistry Curated by ChEMBL					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
C3a anaphylatoxin chemotactic receptor (Homo sapiens (Human))	BDBM50422988 (CHEMBL230034) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Antagonist activity against C3AR in HMDMs assessed as inhibition of C3a-induced intracellular calcium release by Fluo-3 AM dye based FLIPR assay				J Med Chem 57: 8459-70 (2014) Article DOI: 10.1021/jm500956p BindingDB Entry DOI: 10.7270/Q21R6S3N
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair