Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CD44 antigen (Homo sapiens (Human)) | BDBM50008917 (CHEMBL3237627) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 3.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of recombinant human hyaluronan binding domain of CD44 binding to immobilized polymeric hyaluronan by surface plasmon resonance assay | J Med Chem 57: 2714-25 (2014) Article DOI: 10.1021/jm5000276 BindingDB Entry DOI: 10.7270/Q2MG7R2P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
CD44 antigen (Homo sapiens (Human)) | BDBM50008917 (CHEMBL3237627) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 4.00E+5 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity to immobilized recombinant human CD44 hyaluronan binding domain by surface plasmon resonance assay | J Med Chem 57: 2714-25 (2014) Article DOI: 10.1021/jm5000276 BindingDB Entry DOI: 10.7270/Q2MG7R2P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
CD44 antigen (Mus musculus) | BDBM50008917 (CHEMBL3237627) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Binding affinity to immobilized recombinant mouse CD44 hyaluronan binding domain by surface plasmon resonance assay | J Med Chem 57: 2714-25 (2014) Article DOI: 10.1021/jm5000276 BindingDB Entry DOI: 10.7270/Q2MG7R2P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |