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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CDK2/CycE' and Ligand = 'BDBM8070'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDK2/CycE


(Homo sapiens (Human))
BDBM8070
PNG
(2-anilino-4-(1H-pyrrol-3-yl) pyrimidine deriv. 8a ...)
Show SMILES Cc1c[nH]c(C)c1-c1ccnc(Nc2cccc(c2)N(=O)=O)n1
Show InChI InChI=1S/C16H15N5O2/c1-10-9-18-11(2)15(10)14-6-7-17-16(20-14)19-12-4-3-5-13(8-12)21(22)23/h3-9,18H,1-2H3,(H,17,19,20)
PDB

UniProtKB/SwissProt

antibodypedia
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GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
Article
PubMed
50 -42.4n/an/an/an/an/a7.430



Cyclacel Limited



Assay Description
In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...


Bioorg Med Chem Lett 14: 4237-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.06.012
BindingDB Entry DOI: 10.7270/Q2CJ8BPP
More data for this
Ligand-Target Pair