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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CDK2/Cyclin A/Cyclin A1' and Ligand = 'BDBM50307514'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDK2/Cyclin A/Cyclin A1


(Homo sapiens (Human))
BDBM50307514
PNG
(1-Methyl-8-[(pyridin-2-ylmethyl)amino]-4,5-dihydro...)
Show SMILES Cn1nc(C(N)=O)c2CCc3cnc(NCc4ccccn4)nc3-c12
Show InChI InChI=1S/C17H17N7O/c1-24-15-12(14(23-24)16(18)25)6-5-10-8-20-17(22-13(10)15)21-9-11-4-2-3-7-19-11/h2-4,7-8H,5-6,9H2,1H3,(H2,18,25)(H,20,21,22)
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PC cid
PC sid
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Article
PubMed
n/an/a 87n/an/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Inhibition of CDK2/Cyclin A


J Med Chem 53: 2171-87 (2010)


Article DOI: 10.1021/jm901710h
BindingDB Entry DOI: 10.7270/Q2N879W9
More data for this
Ligand-Target Pair